E Wolfgang Kuehn Selected Research

polycystic kidney disease 2 protein

1/2021	Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner.
1/2020	Tubular STAT3 Limits Renal Inflammation in Autosomal Dominant Polycystic Kidney Disease.
1/2020	Divergent function of polycystin 1 and polycystin 2 in cell size regulation.
1/2010	PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation.

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E Wolfgang Kuehn Research Topics

Disease

8	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2020 - 08/2007
7	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2021 - 03/2007
6	Cysts 01/2014 - 12/2002
3	Neoplasms (Cancer) 08/2013 - 12/2006
2	Cystic Kidney Diseases (Cystic Kidney Disease) 01/2021 - 09/2008
2	Situs Inversus 12/2007 - 03/2007
1	Ciliopathies 01/2018
1	Chronic Kidney Failure (Chronic Renal Failure) 12/2015
1	Atypical Hemolytic Uremic Syndrome 07/2013
1	Kidney Neoplasms (Kidney Cancer) 03/2011
1	Kidney Diseases (Kidney Disease) 03/2011
1	Retinal Degeneration 05/2010
1	Bardet-Biedl Syndrome (Syndrome, Bardet-Biedl) 05/2010
1	Polycystic liver disease 01/2010
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 12/2007
1	Hypoxia (Hypoxemia) 05/2007
1	Hydrocephalus (Hydrocephaly) 03/2007
1	Infertility (Sterility) 03/2007
1	Hypersensitivity (Allergy) 12/2006
1	Hepatocellular Carcinoma (Hepatoma) 12/2006
1	Fibrosis (Cirrhosis) 12/2002
1	Ischemia 12/2002

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 01/2020 - 12/2002
4	polycystic kidney disease 2 proteinIBA 01/2021 - 01/2010
3	polycystic kidney disease 1 proteinIBA 01/2021 - 01/2020
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 05/2007
2	TRPP Cation ChannelsIBA 01/2021 - 01/2020
2	Phosphotransferases (Kinase)IBA 01/2018 - 12/2006
2	CalciumIBA 03/2013 - 08/2008
2	Ion Channels (Ion Channel)IBA 03/2009 - 08/2008
1	Peptides (Polypeptides)IBA 01/2021
1	Chloroquine (Aralen)FDA LinkGeneric 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Doxycycline (Periostat)FDA LinkGeneric 01/2021
1	Transient Receptor Potential ChannelsIBA 01/2021
1	calpain inhibitorsIBA 01/2021
1	Galectin 1 (LGALS1)IBA 01/2021
1	Tetracycline (Achromycin)FDA LinkGeneric 01/2021
1	calpastatinIBA 01/2021
1	Lysosomal-Associated Membrane Protein 1IBA 01/2021
1	Galectins (Galectin)IBA 01/2021
1	CytokinesIBA 01/2020
1	ProteomeIBA 01/2020
1	ChemokinesIBA 01/2020
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2020
1	A-factor (Streptomyces)IBA 01/2020
1	Rituximab (Mabthera)FDA Link 12/2015
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 12/2015
1	astrinIBA 08/2013
1	Mechanistic Target of Rapamycin Complex 1IBA 08/2013
1	eculizumab FDA Link 07/2013
1	TOR Serine-Threonine KinasesIBA 03/2013
1	MTOR InhibitorsIBA 03/2011
1	Sirolimus (Rapamycin)FDA Link 03/2011
1	trans-sodium crocetinate (crocetin)IBA 03/2011
1	RoscovitineIBA 08/2007
1	Retinaldehyde (Retinal)IBA 03/2007
1	emt protein-tyrosine kinase (IL2-inducible T-cell kinase)IBA 12/2006
1	LigandsIBA 12/2006
1	InterleukinsIBA 12/2006
1	Tyrosine (L-Tyrosine)FDA Link 12/2006
1	Membrane Proteins (Integral Membrane Proteins)IBA 12/2002

Therapy/Procedure

1	Plasma Exchange 12/2015